Natural Spirillum Minus Infection in White Mice

Experiments on the Spirillum of Rat-Bite Fever

Knowles, Das Gupta and Sen (1936) have observed that 15 of a batch of 31 white mice (Mus muscuius) showed spontaneous infection with Spirillum minus. These mice were caged in cages of narrow meshed iron-netting. No rat could possibly get at the mice to bite them. On looking through the literature it is found that other workers such as Robertson (1930), McCluskie (1930), and lately Francis (1936...

Spontaneous Infection of Guinea-Pigs with a Spirillum, Presumably Spirillum Minus Carter, 1887

McCluskie (1930), Robertson (1930), Francis (1936), and Knowles, Das Gupta and Sen (1936) have noted the occurrence of Spirillum minus in the naturally-infected mouse, Mus musculus. The last-named workers cited an incident in which a wrong diagnosis of rat-bite fever was established on the basis of discovery of spirilla in a white mouse inoculated with the blood of a patient suffering from prol...

Spirillum Minus Infection Acquired from an Indian Squirrel (Sciurus SP.)

A Note on Spirillum Minus (Carter), the Causative Organism of Rat-Bite Fever

Streptomycin and Terramycin in the Treatment of Rat-Bite Fever Due to Spirillum Minus

Successful result in the treatment of ratbite fever with the arsphenamine compounds were recorded by Knowles and Das Gupta (1928) and Chopra, Basu and Sen (1939), among others. The usual treatment to effect complete cure was to give two, preferably three intravenous injections of N.A.B. the doses being 0.3 gm., 9-45 gm. and 0.6 gm. When there was albumen the urine, the drug was administered in ...